Comprises Isaacs’ personal reference library, used by him for in-house reference as well as in press kits. For business, he produced and kept documentation files including drawings, plans and photographs about his designs and copies of any media coverage.

Covers Isaacs' work as Director of Graduate Studies, including Stanley Tigerman's dismissal and supervision of the John Etenza scholarship. It also documents projects not tied to single semesters or classes and contains work by Isaacs’ students. Overlap of content amongst Sub-subseries occurs, because of how Isaacs himself filed the material.

Isaacs own personal and professional notes, written in bound journals, diaries, daybooks, and on loose index cards. At the end of the index cards, a metal clip still holds some of his notes on index cards.

Documents work by Ken Isaacs that was done independent of UIC but completed during his time there. It includes exhibit proposals, contest entries and correspondence.